David A. Jaffray

David Jaffray | Professor
BSc (Alberta), PhD (Western)

Main Appointments

  • Department of Radiation Oncology
  • Department of Medical Biophysics
  • Senior Scientist, Head, Radiation Physics Department, Fidani Chair in Radiation Therapy Physics, Princess Margaret Hospital
  • Director, Techna Institute for the Advancement of Technology for Health (Techna), and Executive Vice President, Technology & Innovation, University Health Network (UHN)

Additional Appointments

  • Institute of Biomaterials & Biomedical Engineering
  • Principal, Image-Guided Therapy (IGTx) Group & Site Leader, Medical Technology Innovation Priority Platform, Ontario Cancer Institute

Contact Information

+1 416 946-2387 (office)
david.jaffray@rmp.uhn.on.ca (email)


Research Theme

Research Interests

  1. Contribution to our understanding of the physics factors limiting the performance of megavoltage radiography systems.  In the period of 1988-1995, Dr. Jaffray produced 4 papers that covered the scope of physical factors limiting the quality of megavoltage radiographs (as used in portal imaging for radiation therapy).  The comprehensive characterization of x-ray source (focal and extra-focal) is a highly cited article that has impacted imaging and treatment planning system design. The development of detailed Monte Carlo and experimental studies on the topics of x-ray scatter and Swank noise are still some of the most comprehensive studies in this area to-date.
  2. The development of portal imaging systems for use in radiation therapy.  During his Ph.D. studies and during his time as a clinical physicist at William Beaumont Hospital, Dr. Jaffray developed the InfiMED (now Cablon Medical) portal imaging systems and Elekta iView portal imaging systems (software and original hardware design).  These are still in use today in an evolved form (over 15 years in use in the community).
  3. The development of kilovoltage cone-beam CT for image guided RT arise from the invention of Dr. Jaffray and colleagues (USPTO) while at the William Beaumont Hospital.  This work was funded in part by the USAMRMC and NIH.  The technology has been licensed to Elekta Oncology systems and cone-beam CT has become the standard for improving the precision and accuracy of radiation therapy throughout the world.  There are approaching ~1000 such systems in the field and they are used every day to direct cancer therapy.  In addition to developing technology, Dr. Jaffray and his team have been working to advance the practice through publication of results and techniques that rely in image-guidance approaches and technologies.  This work has resulted in a sustained demand (>20/year) for invited talks and presentations around the globe on his work.  Research in this area is ongoing with several papers and patentable technologies arising each year.  The original paper by Dr. Jaffray on this development is one of most highly cited papers in the field of radiation therapy.

Select Publications

See current publications at PubMed