Edmond W. K. Young

Edmond Young | Assistant Professor
BASc (UBC), MASc (UBC), PhD (Toronto)

Main Appointments

  • Department of Mechanical & Industrial Engineering

Additional Appointments

  • Institute of Biomaterials & Biomedical Engineering

Contact Information

Office: Mechanical Building (MC), 5 King’s College Road, Room 313

+1 416 978-1521 (office)
eyoung@mie.utoronto.ca (email)
Integrative Biology and Microengineered Technologies Laboratory (IBMT) (web)

Research Themes

Research Interests

Professor Young’s research interests focus on the development of microscale technologies for cell biology applications, with emphasis on creating engineered models that mimic the cell and tissue microenvironments in both healthy and diseased animals.

This interdisciplinary research area requires combining the principles and techniques of microfabrication, fluid mechanics, material science, cell biology, and cell imaging and microscopy.

Select Publications

Hong WS, Young EWK, Tepp WH, Johnson EA, Beebe DJ, “A Microscale Neuron and Schwann Cell Coculture Model for Increasing Detection Sensitivity of Botulinum Neurotoxin Type A” Toxicological Sciences, DOI: 10.1093/toxsci/kft082 [Epub ahead of print] (2013).

Warrick JW, Young EWK, Schmuck EG, Saupe KW, Beebe DJ, “High-content adhesion assay to address limited cell samples” Integrative Biology, DOI: 10.1039/c3ib20224k (2013).

Bischel LL, Young EWK, Mader BR, Beebe DJ, “Tubeless microfluidic angiogenesis assay with three-dimensional endothelial-lined microvessels” Biomaterials, 34(5):1471-7 (2013).

Sackmann EK, Berthier E, Young EWK, Shelef S, Wernimont SA, Huttenlocher A, Beebe DJ, “Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays” Blood, 120(14): e45-e53 (2012).

Berthier E, Young EWK, Beebe DJ, “Engineers are from PDMS-land, Biologists are from Polystyrenia” Lab Chip, 12(7): 1224-1237 (2012).

Young EWK, Pak C, Kahl BS, Yang DT, Callander NS, Miyamoto S, Beebe DJ, “Microscale functional cytomics for studying hematologic cancers” Blood, 119(10): e76-e85 (2012).

Young EWK, Berthier E, Guckenberger DJ, Sackmann E, Lamers C, Meyvantsson I, Huttenlocher A, Beebe DJ, “Rapid prototyping of arrayed microfluidic systems in polystyrene for cell-based assays” Analytical Chemistry, 83(4): 1408-1417 (2011).

Young EWK, Beebe DJ, “Fundamentals of microfluidic cell culture for controlled micro-environments” Chemical Society Reviews, 39(3): 1036-1048 (2010).

Young EWK, Watson MWL, Srigunapalan S, Wheeler AR, Simmons CA, “Technique for real-time measurements of endothelial permeability in a microfluidic membrane chip using laser-induced fluorescence detection” Analytical Chemistry, 82(3): 808-816 (2010).

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